- Labor Organizations, Murphysboro
- Laboratories Dental, Murphysboro
- Laboratories Medical, Murphysboro
- Land Surveyor, Murphysboro - Land Surveying Services
- Landscape Contractors & Designers, Murphysboro
- Landscaping, Murphysboro
- Lawn & Garden Chemicals, Insecticides & Fertilizers, Murphysboro
- Lawn & Garden Decor & Ornaments, Murphysboro
- Lawn & Garden Equipment & Supplies, Murphysboro
- Lawn & Garden Services, Murphysboro
- Lawn Maintenance Services, Murphysboro
- Lawn Mower Repair & Blade Sharpening Service, Murphysboro
- Lawn Mowers & Power Equipment, Murphysboro
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- Lawyers & Attorneys, Murphysboro
- Legal Professionals, Murphysboro
- Libraries, Murphysboro
- Life Insurance, Murphysboro
- Liquor Stores, Murphysboro
- Loans Personal, Murphysboro
- Lodging, Murphysboro
- Lodging Services, Murphysboro
- Long Haul Trucking Companies, Murphysboro
- Lumber & Lumber Products, Murphysboro
- Lumber & Lumber Products, Murphysboro
- Lutheran Church, Murphysboro
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