- Obstetricians & Gynecologists, Effingham - Ob-Gyn Doctors, Physicians & Surgeons (Obstetrics & Gynecology)
- Occupational Health Care Physicians & Surgeons, Effingham - Occupational Medicine
- Occupational Health Care Professionals, Effingham
- Occupational Medicine Doctors, Effingham - Physicians & Surgeons
- Occupational Therapy, Effingham - Occupational Health Specialists
- Office Buildings & Parks, Effingham
- Office Furniture Manufacturers, Effingham
- Office Space on Rent, Effingham - Executive Suites, Meeting Rooms, Conference Rooms, Virtual Offices, etc
- Office Supplies, Equipment & Office Furniture Stores, Effingham
- Oil & Gas Companies, Effingham
- Oil & Petroleum Products, Effingham - Merchant, Wholesalers, etc
- Oil Change & Lubrication, Effingham - Auto Oil & Quick Lube
- Oil Industry & Oil Field Equipment & Services, Effingham - Oil Companies
- Oil Petroleum Wholesale, Effingham
- Oncologists, Effingham - Cancer Doctors, Physicians & Surgeons (Oncology)
- Ophthalmologists, Effingham - Eye Doctors, Physicians & Surgeons (Ophthalmology)
- Optical Stores - Eyeglasses, Lenses & Sunglasses, Effingham
- Optometrists, Effingham - Eye Doctors, Physicians & Surgeons (Optometry)
- Oral Surgeon, Effingham - Dentists - Oral & Maxillofacial Surgeons
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- Ornamental Nursery, Effingham
- Ornamental Nursery Products, Effingham
- Ornamental Nursery Services, Effingham
- Orthodontist, Effingham - Teeth Straightening, Invisalign & Dental Braces
- Orthopedists, Effingham - Orthopedic Surgery Doctors, Physicians & Surgeons
- Orthotics and Prosthetics, Effingham
- Other Attorneys & Lawyers, Effingham
- Other Attorneys & Lawyers, Effingham
- Other Building Materials & Supplies, Effingham
- Other Lawyers & Attorneys, Effingham
- Other Lodging, Effingham
- Outdoor & Lawn & Garden Equipment Repair & Service, Effingham
- Outdoor Advertising & Billboard, Effingham
- Outdoor Equipment & Accessories, Effingham
- Outdoor Furniture & Patio Furniture, Effingham - Garden Furniture Stores
- Outsourcing Services, Effingham
- Overhead Door, Effingham
- Oxygen & Respiratory Equipment & Supplies, Effingham - Oxygen Concentrator, Tank, Machine, etc
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