- Machine Shop & Tool Repair Service, Effingham
- Machinery, Supplies & Equipment - Business Production Related, Effingham
- Machinery, Supplies & Equipment - Business Supplies Related, Effingham
- Machinery, Supplies & Equipment - Construction & Contractor Related, Effingham
- Mailing, Delivery & Courier Service, Effingham
- Maintenance, Cleaning & Sanitation, Effingham
- Major Appliances, Effingham - Household & Kitchen
- Malls & Shopping Centers, Effingham
- Malpractice Attorneys & Lawyers, Effingham
- Malpractice Attorneys & Lawyers, Effingham
- Malpractice Lawyers & Attorneys, Effingham
- Mammography Clinics, Effingham - Breast Cancer Screening
- Management Consultants & Services, Effingham
- Manicurists & Pedicurists, Effingham
- Manufactured & Mobile Home Movers & Transporting, Effingham
- Manufacturing, Effingham
- Marinas & Marina Services, Effingham
- Marriage & Family Counselors, Effingham
- Marriage & Family Counselors Information & Referrals, Effingham
- Martial Arts & Self Defense Schools, Effingham
- Mary Kay Cosmetics, Effingham
- Masonry Materials & Supplies, Effingham
- Massage Therapists & Professional, Effingham
- Massage Therapy, Effingham
- Medical & Health Service Organizations, Effingham
- Medical Diagnostic Clinics, Effingham - Clinical Labs & Centers
- Medical Supplies & Equipment, Effingham
- Membership Sports & Recreation Clubs, Effingham
- Mental & Developmental Information & Referral Services, Effingham
- Mental Health Clinics, Effingham - Treatment Centers
- Mental Health Specialists, Effingham - Psychologist, Psychiatrist, Psychotherapist, etc
- Merle Norman Cosmetics, Effingham
- Metal Buildings, Effingham - Wood Buildings
- Metal Buildings, Effingham - Kits, Homes, Steel Buildings, etc
- Metal Repair Service & Blacksmith, Effingham - Iron Works
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- Methodist Church, Effingham
- Mexican Restaurants, Effingham
- Midwives, Effingham
- Mildew Removal & Control, Effingham - Mold Removal
- Mini & Self Storage, Effingham
- Mini Golf Courses, Effingham
- Mirrors, Effingham - Custom, Framed, Bathroom, Vanity & Wall Mirrors
- Miscellaneous Business Product Repair, Effingham
- Miscellaneous Government, Effingham
- Miscellaneous Industry, Effingham
- Miscellaneous Personal Services, Effingham
- Miscellaneous Photographers, Effingham
- Miscellaneous Professional, Effingham
- Mobile Home Contractors, Effingham
- Mobile Home Improvements & Repairs, Effingham
- Mobile Home Parks & Communities , Effingham
- Modular & Mobile Homes For Sale, Effingham - Manufactured Homes Sale & Service
- Monuments, Tombstones, Markers & Memorials, Effingham
- Mortgage Bankers & Correspondents, Effingham
- Motor Vehicle, Effingham
- Motor Vehicle Rental & Leasing, Effingham
- Motorcycle & Motor Scooters Dealers, Repair & Service, Effingham
- Motorcycle Parts, Accessories & Dealers, Effingham
- Motorcycle Repair & Service, Effingham
- Movie Theaters, Effingham
- Moving Companies, Effingham
- Moving Supplies & Equipment Rental, Effingham
- Moving Truck Rental , Effingham
- Mulch, Peat & Moss Products, Effingham
- Music, Effingham
- Musical Instrument Manufacturers, Effingham
- Musical Instrument Rental, Effingham - Band & Orchestra Instruments
- Musical Instruments & Equipment Stores, Effingham
- Musical Instruments - Guitars, Effingham
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